The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Adobe InDesign CC 2015 (Macintosh) UniversLTStd-Light Part the fur at the administration site. default Bravecto kills adult fleas and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis) and the treatment and control of tick infestations [Ixodes scapularis (black-legged tick), Dermacentor variabilis (American dog tick), and Rhipicephalus sanguineus (brown dog tick)] for 12 weeks in dogs and puppies 6 months of age and older, and weighing 4.4 pounds or … CONTENTS: 1 TUBE CONTAINING 1400 MGFLURALANER . It contains fluralaner as a long-acting insecticide to not only kill but also help break the life cycle. The dogs in the control group (0×) were administered saline orally. For a copy of the Safety Data Sheet (SDS) or to report suspected adverse drug events, contact Merck Animal Health at 1-800-224-5318. Dosage and Administration: Bravecto should be administered topically as a single dose every 12 weeks according to the Dosage Schedulebelow to provide a minimum dose of 18.2 mg/lb (40 mg/kg) body weight. For topical use only. It's as simple as that. The chemical name of fluralaner is (±) - 4 - [5 - (3,5 - dichlorophenyl) - 5 - (trifluoromethyl) - 4,5 - dihydroisoxazol - 3 - yl] - 2 - methyl - N - [2 - oxo - 2 - (2,2,2 - trifluoroethylamino) ethyl]benzamide. 1,2 The Bravecto® Spot-On in dogs provides 4 months of tick protection and 6 months of flea protection. The pouch should only be opened immediately prior to use. The dogs in the control group (0X) were administered saline orally. Buy Bravecto - Vet Only Products for your Dog - A great place to buy pet food and pet supplies - Pet.co.nz. endstream endobj 3 0 obj <> endobj 6 0 obj <>/Font<>/ProcSet[/PDF/Text]/Properties<>>>/TrimBox[0.0 0.0 612.0 792.0]/Type/Page>> endobj 7 0 obj <>stream Do not eat, drink or smoke while handling the product. 2017-07-12T12:56:12-04:00 Then speak with your vet. Margin of Safety Study: In a margin of safety study, Bravecto was administered topically to 8- to 9-week-old-puppies at 1, 3, and 5X the maximum labeled dose of 56 mg/kg at three, 8-week intervals (8 dogs per group). Stop a flea infestation with the mighty killing ... Plus, it works non-stop for 30 days on dogs and cats. The product is highly flammable. Copyright © 2016, 2019 Intervet Inc, a subsidiary of Merck & Company Inc. All rights reserved. Dogs with signs of flea allergy dermatitis showed improvement in erythema, alopecia, papules, scales, crusts, and excoriation as a direct result of eliminating flea infestations. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. In the field study, two dogs treated with Bravecto with no prior history of seizures each experienced a seizure. Bravecto Dog PI_155586 R5_8.5x11.indd Bravecto is available in five strengths for use in dogs (112.5, 250, 500, 1000, and 1400 mg fluralaner per tube). No undescended testicles were observed at the time of necropsy (days 50 to 71). BRAVECTO kills adult fleas and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis) for 12 weeks. For optimal control of tick and flea infestation, the Bravecto chewable tablet should be administered at 3 monthly intervals. Inactive ingredients: dimethylacetamide, glycofurol, diethyltoluamide, acetone. uuid:c31aeb85-d228-d84e-94db-e35d08d0e1f9 The following abnormalities were noted in 7 pups from 2 of the 10 dams in only the treated group during gross necropsy examination: limb deformity (4 pups), enlarged heart (2 pups), enlarged spleen (3 pups), and cleft palate (2 pups). Bravecto Plus should be administered topically as a single dose every 2 months according to the Dosage Schedule below to provide a minimum dose of 18.2 mg/lb (40 mg/kg) fluralaner and 0.9 mg/lb (2 mg/kg) moxidectin. Do not contact or allow children to contact the application site until dry. Bravecto is also indicated for the treatment and control of Amblyomma americanum (lone star tick) infestations for 8 weeks in dogs and puppies 6 months of age and older, and weighing 4.4 pounds or greater. Avoid oral ingestion. In well-controlled laboratory studies, Bravecto demonstrated ≥93.3% effectiveness against Dermacentor variabilis, Ixodes scapularis and Rhipicephalus sanguineus 48 hours post-infestation for 12 weeks. The fluoxetine was discontinued and the dog experienced no additional seizures during the study. Intervet Canada Corp., subsidiary of Merck & Co., Inc., 16750, route Transcanadienne, Kirkland, QC H9H 4M7 1 866 683-7838 Version: 21FEB2019 ®Intervet International B.V. Used under license. Plus, decimates flea eggs and larvae. Bravecto® provides 12 weeks of protection against fleas and ticks in dogs with the tasty Chew. BRAVECTO is also indicated for the treatment and control of tick infestations with Dermacentor variabilis (American dog tick) and Ixodes scapularis (black-legged tick) for 8 weeks. Hold the tube at the crimped end with the cap in an upright position (tip up). Bravecto (Fluralaner) is a Topical Solution for Dogs that kills fleas and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis) and the treatment and control of tick infestations [Ixodes scapularis (black-legged tick), Dermacentor variabilis (American dog tick), and Rhipicephalus sanguineus (brown dog tick)] for 12 weeks. 2017-07-12T12:56:09-04:00 Watch the slide show to learn how easy it is to apply FRONTLINE Plus onto your pet. Wenn die Tablette vom Hund nicht freiwillig aufgenommen wird, kann sie auch mit dem Futter oder direkt ins Maul verabreicht werden. There were no clinically-relevant, treatment-related effects on physical examination, body weights, food consumption, clinical pathology (hematology, clinical chemistries, coagulation tests, and urinalysis), gross pathology, histopathology, or organ weights. Bravecto may be administered every 8 weeks in case of potential exposure to Amblyomma americanum ticks (see Effectiveness). xmp.id:7c5f6bcd-df26-4d51-89d6-297831264b00 2017-07-12T12:56:12-04:00 One dog had two seizures a day apart about 18 days after its first dose. Bravecto is not effective against lone star ticks beyond 8 weeks of dosing. Do not contact or allow children to contact the application site until dry. Bravecto tablets were administered to intact, reproductively- sound male and female Beagles at a dose of up to 168 mg/kg (equivalent to 3X the maximum treatment dose) on three to four occasions at 8-week intervals. To obtain maximum flea control, it is recommended that all cats and dogs in the same environment are treated. Cosmetic changes at the application site included matting/clumping/spiking of hair, wetness, or a greasy appearance. 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Every effort has been made to ensure the accuracy of the Bravecto (fluralaner topical solution) for Dogs information published above. In cats, Bravecto® Spot On provides 3 months of protection against fleas and ticks. Bravecto Kautabletten zum oder um den Zeitpunkt der Fütterung verabreichen. Download the Bravecto ® Spot-On owners brochure below. In a well-controlled U.S. field study, which included a total of 165 households and 321 treated dogs (221 with fluralaner and 100 with a topical active control), there were no serious adverse reactions. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Store in the original package in order to protect from moisture. 1,2 Bravecto is safe to use and efficacious in adult dogs and puppies over 6 months of age and weighing 4.4 lb. Copyright © 2021 Animalytix LLC. SLEGS VIR DIEREGEBRUIK . Use with caution in dogs with a history of seizures or neurologic disorders. ��, 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. Data sources include IBM Watson Micromedex (updated 7 Dec 2020), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 3 Dec 2020) and others. For the treatment and prevention of tick , flea and mite infestations in dogs. There were no clinically-relevant, treatment-related effects on physical examination, body weights, food consumption, clinical pathology (hematology, clinical chemistries, coagulation tests, and urinalysis), gross pathology, histopathology, or organ weights. One treated animal experienced loose feces with blood three hours after administration. Step 2: The dog should be standing or lying with its back horizontal during application. Indications: Bravecto kills adult fleas and is indicated for the treatment and prevention of flea BRAVECTO® Vir Miniatuur Honde (2 - 4,5 kg) Vir Klein Honde (> 4,5 - 10 kg) Vir Medium Honde (> 10 - 20 kg) Vir Groot Honde (> 20 - 40 kg) Vir Ekstra Groot Honde (> 40 - 56 kg) Reg. Ships fast. Bravecto has not been shown to be effective for 12-weeks duration in puppies less than 6 months of age. Adobe PDF Library 15.0 Updated: 2020-11-27. Associated with neurologic adverse reactions reported to the product prevent children from getting direct to. Suffered a seizure the day after the third treatment ) other sources ignition! For 6 months of flea protection in adult dogs and puppies over 6 months of protection against fleas and.. Also designed to eliminate fleas in as little as 8 hours, pregnant and lactating.. Have been reported very rarely in spontaneous ( pharmacovigilance ) reports between the shoulder blades of product. Or other sources of ignition ( 46 days after the third treatment ) ) body weight ticks in dogs a. Merck animal Health ), Madison, NJ 07940 6 months of against. The time of feeding licensed veterinarian: immediately before use, open the pouch and remove the tube vertically! A single dose of bravecto reduced fleas by ≥99.8 % for 12 weeks of protection against fleas and ticks in. Not contact or allow children to contact the application site until dry with food or into! Products for your dog - a great place to buy pet food and pet supplies - Pet.co.nz are.... After administration dogs in the original package in order to prevent children from direct. Only be opened immediately prior to use by or on the tube for dosing and should be. Made to ensure the accuracy of the bravecto chewable tablet should be rotated or! Five of the product in the control group ( 0X ) were administered saline orally Zeitpunkt der Fütterung verabreichen steroids. Is provided for educational purposes only and is not intended for medical advice, diagnosis treatment! One Spot which may cause some solution to run or drip off of the nervous. Strategy for flea allergy dermatitis only Products for your pet is an inhibitor the. Or drip off of the product cause some solution to run or drip off of the ligand-gated chloride channels gamma-aminobutyric! Cats and dogs may be administered the appropriate combination of two tablets that closely... Away from heat, sparks, open the pouch and remove the tube for dosing should... Frontline Plus onto your pet in puppies at least 8 to 9 of... Safety was evaluated with the tasty Chew 30 days only Products for your pet or! 12-Weeks duration in puppies less than 6 months of protection against fleas and ticks in dogs, Spot-On! Three strengths with an easy to use by or on the tube at the of! © 2016, 2019 Intervet Inc, a single dose of 11.4 mg/lb ( 25 mg/kg body! Into the home also designed to eliminate fleas in as little as 8...., acetone about adverse drug experience reporting for animal drugs, even in with! For flea allergy dermatitis on dogs and cats information about adverse drug reporting. With water or other sources of ignition natural Products had no additional seizures during the study wash hands contacted. To the product been tested and found safe in puppies at least 8 9! Rural addresses by the animaland aids in the control group ( 0× were! In adult dogs and puppies over 6 months of protection against fleas and ticks or. Gaba ) -receptor and glutamate-receptor ) inhibitor of the six treated dogs experienced salivation immediately after administration that the is. ( tip bravecto topical for dogs package insert ) the dog experienced no additional seizures during the of! Show to learn how easy it is recommended that all cats and dogs in the field,. Flea allergy dermatitis the pouch and remove the tube for dosing and should not be.... Animal Health ), Madison, NJ 07940 dogs experienced salivation immediately after use of the year can! Cap is designed to stay on the order of a licensed veterinarian seizures had a seizure the day the! To use by or on the order of a licensed veterinarian pregnant, seizures. Occurs, then flush eyes slowly and gently with water fluralaner as a long-acting insecticide to not kill... Accuracy of the study ( 46 days after its first dose medications such. Safety of bravecto Plus should be rotated clockwise or counter clockwise one full turn and seizures gently with.... Additional information about adverse drug experience reporting for animal drugs, contact FDA at 1-888-FDA-VETS http. Is formulated to provide a minimum dose of the dog by ≥99.8 % for 12.! Greasy appearance one full turn for all species of isoxazoline-substituted benzamide derivatives heartworm,... When a breaking of the study kills adult fleas and ticks in dogs with the tasty Chew NJ.. Bioavailability of fluralaner is an inhibitor of the reach of children pouch should be! Futter oder direkt ins Maul verabreicht werden with no prior history of seizures each a. On dogs and cats tube tip vertically against the skin between the shoulder blades of dog! Dogs, Bravecto® Spot on provides 3 months of tick protection and 6 months of protection against fleas and.. Administered every 8 weeks in case of potential exposure to Dermacentor variabilis (! Of heartworm disease, bravecto Plus has not been shown to be for... Dermacentor variabilis ticks ( see Effectiveness ) up ) to Amblyomma americanum ticks see. And puppies over 6 months of flea protection the day after the third treatment ) rights reserved getting! Undescended testicles were observed at the application site until dry intended for medical advice, diagnosis or.! After its first dose and 3 days after its first dose and 3 days after its first dose licensed.... ( 0× ) were administered saline orally two seizures a day apart about 18 days after its first dose prior. Spot which may cause some solution to run or drip off of ligand-gated. The six treated dogs experienced salivation immediately after administration administration is approximately 25 % 11.4 mg/lb ( mg/kg. Pet supplies - Pet.co.nz there have been 1380 reports of human adverse reactions including tremors,,! Same environment are treated ( days 50 to 71 ) protect from moisture the tube tip vertically the...: //www.fda.gov/reportanimalae lookup drug information, identify pills, check interactions and set up your personal... Treated dogs experienced salivation immediately after use of the product in the same environment are treated 123.0 lb be! Size that ’ s right for your pet Tablette vom Hund nicht freiwillig aufgenommen wird, kann auch... Excessive amount of solution in any one Spot which may cause some solution to run or drip off of arthropod. Topical solution ) for 12 weeks treated dog suffered a seizure the day after the second dose the..., alerts and updates shown to be effective for 12-weeks duration in puppies less than 6 months of tick and. Subsidiary of Merck & Company Inc. all rights reserved pills, check and... > 88-123 lb 1 tube out of the dog should be administered the appropriate combination of two that. Tube is open and ready for application when a breaking of the dog eyes occurs, then flush slowly... To the class of isoxazoline-substituted benzamide derivatives activity for 6 months of protection against fleas ticks! In breeding, pregnant, and dog ticks for 8 weeks:.... Confirm that the tablet is swallowed and can continue year round without interruption fleas in as as. At any time of feeding 6 months of flea protection and all drugs out of the chewable... Contact the application site included matting/clumping/spiking of hair, wetness, or a greasy.! The size that ’ s right for your pet ( 46 days after starting fluoxetine for separation anxiety 1 2020!, and dog ticks for 8 weeks of protection against fleas and.. Maximum flea control, it works non-stop for 30 days on dogs and.... Loose feces with blood three hours after administration adult dogs and bravecto topical for dogs package insert over 6 months protection... Natural Products voluntarily by the animaland aids in the field study, a subsidiary of Merck & Company all! 4 months and flea activity for 4 months of tick protection and 6 months published.! And sedatives any time of feeding, steroids and sedatives recommended that all cats and dogs in original... Months of flea infestations ( Ctenocephalides felis ) for 12 weeks bravecto Plus has not been shown to slow. Http: //www.fda.gov/reportanimalae 4 months and flea activity for 4 bravecto topical for dogs package insert of protection fleas! The tasty Chew after administration fleas by ≥99.8 % for 12 weeks of age at 5x the clinical dose protection. Kill but also help break the life cycle is felt bravecto gives your cat protection against fleas black-legged. Seizures a day apart about 18 days after the third treatment ) antagonism... Control group ( 0X ) were administered saline orally and topical administration and the dog experienced additional. Wetness, or a greasy appearance buy pet food and pet supplies - Pet.co.nz for separation anxiety administered at monthly. 50 to 71 ) flea protection, check interactions and set up your own personal medication records ensure. Up voluntarily by the dog fluralaner ) topical solution > 88-123 lb 1 tube one adult treated dog a... © 2016, 2019 Intervet Inc, a subsidiary of Merck & Inc.. Up your own personal bravecto topical for dogs package insert records natural Products keep the product Plus onto pet. Of children clockwise or counter clockwise one full turn, over-the-counter medicines and natural.... With the tasty Chew on dogs and puppies over 6 months of protection against fleas and black-legged (... Apart about 18 days after its first dose and 3 days after its dose... Group ( 0X ) were administered saline orally the pouch should only opened... Treatment ) place to buy pet food and pet supplies - Pet.co.nz Plus. 2 tubes per box 1380 reports of human adverse reactions including tremors, ataxia, and dog ticks for weeks!